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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74696a389ead5c08510701ae003081cf25414a2a8251bc01a0d2d874dffb8fca' 
  AND token = 'y1GGQh7GhEBg++3dFgYh7Cxl2gDD1Z/k2ZeyUKlgwf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}