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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcd9141be0b359e9208b474d298cb37669d8bdc162e14f22d8373959b9de25f8' 
  AND token = 'rCd+1iw3HrOpNmxFq77Fgn+8b4lvyejW4KHFfMkfO7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}