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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16eaeac527d15e35a3c94f3df5b615a3c16d9b690a8fb4b0648813aabdb3d2da' 
  AND token = 'nuvLKLCLHa2/NVCo3WGvYoKBRipm5eNO485T/RgDGdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}