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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e266518ea158cea383be0f3bed4639eb2d7491ad2207b117d620666d3ed5a34' 
  AND token = 'eZGwp2Yy10NxMGML93Piiho2FqwgbjFAWXH1xaBcj5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}