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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9adb2346337431b5eb00f8f2b60b991fb40df36e9615a1c1a327c252c31b7d08' 
  AND token = 'T8AzIQFsjMrY1gj5C8SSHP2ju4zdqGDv0Ib08g/mqDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}