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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ec939e1bdeab2d61e05bd31620bbf678a157259f4c5ce9688d3aca3058dd1e' 
  AND token = 'hr4Zmdo6Bp8ASP+EXV6BRJu101ahXuc18K2YxdbFPXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}