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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c4879ae31336680e30e736645579c9e99e39637760ca177ab27c48d2ccb7832' 
  AND token = 'EnQ1AUr4mqCrrknoiYh9C6Sn8SbAugTOk+JQlnZvx7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}