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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85c52827fcdd9ba231524a73d76a812b55a9294f736ba2d69fcaecdac0cc4cc5' 
  AND token = 'JG2q976Pis4X7HR0RcNH3ROoSf6VS0LCGQ8ZIm5VezE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}