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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6905cd2df80703e1e3b943aeec4a8bef9bbcaa797473022beadd7c781fdd817' 
  AND token = '2almDY0p6EL76z4+Z4jIEl7h1lbMGIGE9n8xtgZ3Xag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}