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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54f9aa450d4f69d3b94ed7599bc64afbca38aa8250360eec46032b18b8d13a64' 
  AND token = 'vEvG8ZqfEQAySrmZiemLzZZWCuanPflUsa1GTD+ugU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}