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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54deac4aa7aa2a6a49ac592711f6ab48538211987782c25e5208286c21f67770' 
  AND token = 'I7Gkmtqaa5HJgH8cxVUMAb44puADdAr3KAm3QX0d8O0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}