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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd376201d8e119a222a6362c43ebd3e89945c8a96951cdf151f149596f87a9cac' 
  AND token = 'VYNRHZWxfCrBzNxlsUvI608GA+42//CUplRykGseAVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}