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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4936094fe9dc77af180aa2fead29500cf003728c6b1fe842ebf3d40845e2ee03' 
  AND token = 'gyERo4Gzq+ykJi9bIipbDc+bpBM1KO9qLxA5hL6ZVbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}