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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c681d392262342ede0d5de6af50767720b9e64fb4d96eb722c9c2c63751b426b' 
  AND token = 'K6xe0MxNmcX3+Tx+gdUEH3TWXSyGHBpnyTxBX5hnaCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}