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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0858867e2d324c21a268bdbdc11c48b0fa18d038bca3549b3fa084f0246a854' 
  AND token = 'D2Fj/FvmUc25sBTzfogFurGu8vjAR4akQnK/a8C+CuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}