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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa400fedc893706183bd82efdefd4bc0ee03a3cafbf35d5232cd5f80fe061b1' 
  AND token = '3W3RMwD3tlWRDQ3koiS4CwcOWFHmAV12vZQeBfTjyYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}