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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8d1e24867b50812d10e319e4127684a1eb8458efd8ae8e4c0c0b4381fced1fd' 
  AND token = 'ob10z99+2a2nKTWjH1o/WzG9ZD1Zj8Z0keZF+yyCmR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}