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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c5d06ee3b6fc05cfdcd00d1344e351ce133ae391ec3954baf5ec075cfb55f57' 
  AND token = '4N174/CMEARDu1cKQOsyjXoTiB4TLRpqNaIYOH731HI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}