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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c97707abf48533af4c5090dfe3a50907fb1d17bd60756baec2d0d348d39fdfa' 
  AND token = '1XIFi/15Ui9N/uaQH3QK+2gaGgog0yvSpFtS5mFd9SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}