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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dd488b24e9cda8cc17031debfe20a547b6b21bd3cc06b41290e588d0db01cdc' 
  AND token = 'Y0KCPZemBPnx3EO6FoxrY5Om7cwUwxE3HqvQI7ZgccI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}