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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '370443d37f50e6926ae5cf0532c4b895dad75335be730a74db790d2879f0ba5c' 
  AND token = '8D3djtTnynWNQB3YcHxs8FoMLWz5SRAHznvYBRvbWOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}