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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b7c1caff733dccf087d504578e1d5dd9948133c8793a4cde98f9c989c7a9458' 
  AND token = 'OTVt11ybk/NrBnK2KHWgFxPUpQ8EM+UpVOjN4KI1oZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}