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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e7e515548f8023495bb13016113b34407aa8bde448acc3c5ea2f851caf13900' 
  AND token = 'rGS9iMKf58HGMVZGKT/tlnqrf0xFIYhHPcCQauTnkK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}