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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65cfd500466350cd8bab2df7386c3e77a656c193d06d72fe9163f6ed8332c493' 
  AND token = 'ucx/MOv7ColV/zTq/UIuoBsiV9tUctr8UvWW0sj/We0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}