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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5b474b7511b0bbe1cb923d1e4c661b30d8f872418aaee731c5c46fd7201da61' 
  AND token = '8cuI/BYcg8BjnMqK7s5psPp8OCQWiaP/Pj7QLuG+vdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}