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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f3421315b8dbd51dc97f815277cbafacfb9cee03e520f9b5c819adc2e78aa65' 
  AND token = 'x49yr1AyWpahv9pAxWGoVbBnvn2PT/mRC1bP8swymi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}