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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff59509c12f37a2698557ed4566a506fb05d684a65fcbf131f35ca676ed70ad' 
  AND token = 'E/VCgTQoHmOmofzfxKz4V5ibc82d5sp7nDZN6yglC9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}