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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddf177a38b2ac9ae126080d99816acc4b1bbc0f63971ddd6c28be1e8aed4628a' 
  AND token = 'aKx5Mx/Y1DMVVAG4KgckHPKneljtyTldHh8gWk35r00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}