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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bac8ce2ec54933389126daf1fc214bc7b80dd7f490533c1c391d04fd79d13571' 
  AND token = 'jCoccigBpTwbTslo/zCPTcZuCY9E9paHtavroFYgotg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}