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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2a89691d15b2ff5ab5480e0ed1fd7ce578519d49ddb63cdc2a1e71904df035c' 
  AND token = 'RedUZNjHhRY/SM72n2mkY8LewXfz3t1sSWXB8JSia5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}