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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c68994f123b9e1080c1559f7c0c6e8af7849d64c3d51f90cd2e0629d2a316d5e' 
  AND token = '+GDM2FNV3m+vAEyE8LD/rFIQgTQOPh2cwiGkQIFE+NQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}