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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a403e93630afbcf665b72672a3e9c93338a74be5069844cd63928229ae4a419' 
  AND token = '+gwjm/3cmI7M+IC+f2xa0PQK/S5yHiGUU8Eq3E56x7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}