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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28c63b8f60a92e6a86f1bc81c15e425cabe0eafc793c81f6f5460f170a7b4167' 
  AND token = 'N91XRYlWnDiytlO1AsQ2wjVDYc+MQwKBBtXqW/bJo/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}