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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f34236d2ea7670f7ab95fd2fa2b2ed14803d3f5d9ddab55940b21ab7a7aa6aa2' 
  AND token = 'UTGQNkZPIjr8CbLsRR4Yw+74XCWSePc3StP4J1Ywckc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}