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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f16821c2e11df4c86e8f92d7dde21a98ffe2f37c7c75d312f3997850e878126' 
  AND token = '6FKN8Bsx5P05x7la1lEKG1uI55zu4/XnCl5P1NdsHqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}