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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5b1a09797877dbfa250422b68678be0b1d6e9f5c98e16865bfbea40220eccb' 
  AND token = 'g+ZpcqAqb/Gqfe5AA9JZHtdGMDWrtAvfZ96KJIUXrx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}