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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccedd1e22d56146cde331823f203db8894150c643ff9a10ab065ce24507e9f5c' 
  AND token = 'yIli39HthVdkLAnkZkN23feB1UewyCim9/h9H7Sf09E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}