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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aa0598163d0de3d5de612bbfeb4efa01f4a2a6d0797866e4a9a5b24ff9bead1' 
  AND token = 'QCDMr6D6VszJwveGfCCqIGCZr25bp3OT7PNmn8qi7Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}