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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f6c2a450332cc1213bb65c5f9bbe8e2e662637b18ae94c30d6450a527260c54' 
  AND token = 'x1NnTQnOcZNby1f/H/Oug1h00+2I6hH8RXBgENEzFFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}