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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b1b3a6dfbebab4725e95a3c87ecdb0dd90cfdf7f42560b9406623a3889960f2' 
  AND token = 'War8Ns6YrjoH1zyUHANF3Mes1ypNW2OkZo5Cl+BnM5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}