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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8f586b28e636fa103c524176f5dcf36374fb23d6b9103239d879376e0b7641d' 
  AND token = 'pEHtiqr0F6y90bM331RHXQbj/WYF4AuGFsZ1ZmuRPlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}