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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d22274151da6c70d81463023a321b469f45f575932df2c9e7ea7a28194c1564' 
  AND token = 'hoKRUiUhjz3JvlcF2+Tp4+0OkRKSDEHxF19132dMVvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}