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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c38642c51c8681b570d3981269c376a8603f4a7d7433c4c1f308f26ba9c6090' 
  AND token = 'VBjVIbI05KuTA54jhujcgyzIsa25H6AKyFFqUWbYTP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}