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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '572e9571d45f523b2af35c2bb7e0690eac9095f82edad43b5b8a3cfecc1afe16' 
  AND token = 'V26y/w6pvwi6LhMGP4j+JvQfIw8+wsk+hn+3RyNm5cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}