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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59744c4813f7ee88a14781118275c71f8d9861df37de0aa998d04474d7ee0bc1' 
  AND token = 'cp0PtH/DQfpR0bkESC1fVhwsY3VsHPEDrqbD9FK/m84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}