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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '780acca60e9d405178022b4773aad15d96d119d3749b0d4fc3a280845da0cd45' 
  AND token = '2nmycVw4PRaolpcPwNIaEpnaXwVDGzHQ8rB1EQDNK18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}