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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f542b144ac18713f249cf5a62199bfba70854e6e0739306f605139f4e86a987f' 
  AND token = 'XnXzOgnrW2YGtX6MZoubEcL6Ovo1+BMuvsm10HG8+rE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}