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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fe9b8a00e098800c1d87f3c9020b65cb050f695a51725f46ee7c91b86f2bf21' 
  AND token = 'o1qe7D4dQxrk6zruGr+ML47hr/jaliCaKZeFNw+B5uA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}