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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e80d6af8bc4c9c845fe4fbe636e9f1311640ae42037cab8b737fc434aab2c549' 
  AND token = 'ek7PzzODC6QPZJpNxK4himKhumEZfSzEAnUmddGB9z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}