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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9044e85736f646c8078f1442c80c88f9f09e823afeab2dfac5c3a50ecbfa0ed8' 
  AND token = 'tyFm0DThHQoXtrhLismZhZLaok7lIS3vHjDFvZoS1RI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}